Transmembrane Prediction

The transmembrane region is the region of the protein sequence that spans the cell membrane. It is usually an α-helical structure with about 20-25 amino acid residues. Most of the amino acids that constitute the transmembrane protein are hydrophobic amino acids. It is very necessary to predict the transmembrane region of the sequence. Generally, membrane proteins cannot be expressed in a prokaryotic expression system. If the transmembrane region is predicted for the sequence and there is a transmembrane region in the sequence, then the eukaryotic expression system needs to be selected for expression in the follow-up.

Overall solutions

Now, CD ComputaBio provides you with professional transmembrane prediction services to meet your scientific research needs.

Methods used in Transmembrane prediction service provided by CD ComputaBio, include:

• Hidden markov model
• Statistical analysis of known database
• Dense alignment surface (DAS) method
• Machine learning method

Result analysis service

There are three values in the prediction results of the transmembrane zone: Inside, Outside, and Transmembrane.

• Inside represents the intracellular region. The larger the value of inside, the greater the possibility that the amino acid is located in the intracellular region.
• Outside represents the extracellular region. The larger the value of outside, the greater the possibility that the amino acid is located in the extracellular region.
• Transmembrane represents the transmembrane region, the larger the value of Transmembrane, the greater the possibility that the amino acid is in the transmembrane region.

Our advantages

• CD ComputaBio provides you with one-stop transmembrane prediction service. We provide a variety of transmembrane prediction methods for flexible choices. We will tailor an exclusive solution for you according to your testing purpose and budget.
• Our research supervisor and project manager will complete your project on time and meet your requirements through open communication channels.
• CD ComputaBio has established a professional after-sales service team to provide customers with efficient, fast and practical solutions.

Services items

CD ComputaBio's transmembrane prediction service can reduce the cost of subsequent experiments. Transmembrane prediction service is an important and necessary step in the process of drug discovery and development. Transmembrane prediction service is a personalized and customized innovative scientific research service. Before determining the corresponding analysis plan and price, each project needs to be evaluated. If you want to know more about service prices or technical details, please feel free to contact us.