Services

Fig 5. Machine learning vs Artificial intelligence vs. Deep learning

CD ComputaBio is a leading provider of AI-based enzyme-catalyzed metabolic engineering design services. With our state-of-the-art technology and expertise, we offer innovative solutions to optimize metabolic pathways and enhance the production of desired compounds, ranging from biofuels and pharmaceuticals to fine chemicals and agricultural products. AI-based enzyme-catalyzed metabolic engineering design involves the use of machine learning algorithms and computational models to optimize and predict metabolic pathways. This approach integrates genetic information, enzyme characteristics, and biochemical knowledge to efficiently design enzymes and metabolic networks for enhanced product synthesis. Through the fusion of AI techniques with biochemical principles, it becomes possible to tackle the complexities inherent in metabolic engineering and accelerate the development of biotechnological applications.

Our Services

In our AI-based enzyme-catalyzed metabolic engineering design services, we employ a wide range of AI techniques to assist in the optimization and prediction of metabolic pathways. Our services include:

Pathway Optimization

Pathway Optimization

We optimize metabolic pathways to maximize the production of desired compounds by identifying key reactions, balancing metabolic fluxes, and selecting appropriate enzymes.

Enzyme Design and Improvement

Enzyme Design and Improvement

Using AI algorithms, we design and engineer novel enzymes with improved catalytic activity, substrate specificity, and stability, allowing for enhanced production efficiency.

Substrate and Product Analysis

Substrate and Product Analysis

We analyze substrate utilization and product formation to identify bottlenecks and propose strategies for improving yield, purity, and selectivity.

Metabolic Network Modeling

Metabolic Network Modeling

By constructing and simulating metabolic network models, we predict the behavior of engineered pathways, allowing for optimization and control through computational simulations.

Our Analysis Methods

To ensure accurate and reliable results, we employ advanced analysis methods in our AI-based enzyme-catalyzed metabolic engineering design services. Our analysis methods include but are not limited to the followings:

Machine Learning Algorithms We utilize a variety of machine learning techniques, such as artificial neural networks, genetic algorithms, and random forests, to model enzyme activity, predict metabolic fluxes, and optimize pathway designs.
Structural Bioinformatics Using computational tools, we analyze enzyme structures, predict binding affinities, and identify key residues for mutagenesis to enhance enzyme performance.
Knockout and Overexpression Through genetic manipulations guided by AI algorithms, we perform knockout or overexpression experiments to validate model predictions and optimize pathways in living organisms.
High-Throughput Screening We employ high-throughput screening techniques to evaluate enzyme libraries, identify improved variants, and select the most promising candidates for further optimization.
Artificial Neural Networks (ANN) ANNs are used to model enzyme activities, predict metabolic fluxes, and optimize pathway designs based on training data.
Genetic Algorithms (GA) By applying principles of natural selection and genetic inheritance, GA optimizes metabolic pathways and enzyme characteristics through iterative design and selection processes.

Why Choose Us?

Fig 6. Why Choose Us?

With our cutting-edge technology and extensive knowledge, CD ComputaBio excels as a prominent supplier of AI-driven services for designing enzyme-catalyzed metabolic engineering. If you are interested in our services or have any questions, please feel free to contact us.

Reference:

  • Lawson C E, Martí J M, Radivojevic T, et al. Machine learning for metabolic engineering: A review[J]. Metabolic Engineering, 2021, 63: 34-60.

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