Welcome to CD ComputaBio, as a leader in computational biology, we take pride in offering cutting-edge in silico protein design services that leverage advanced computer simulations to innovate protein engineering. Our mission is to empower researchers, pharmaceutical companies, and biotechnology firms by providing tailored protein design, optimization, and modeling solutions.
Drug Discovery and Development
Once a lead compound is identified, we assist in optimizing its efficacy, selectivity, and pharmacokinetic properties through iterative modeling.
Enzyme Engineering
The field of enzyme engineering has greatly benefited from in silico design methods. By analyzing enzyme structures, we can predict how modifications will affect their catalytic properties, stability, and specificity.
Synthetic Biology
Simulating and optimizing entire metabolic pathways for enhanced production of biofuels, pharmaceuticals, or biochemical products.
Enzyme Design
We utilize machine learning algorithms to predict enzyme properties, substrate preferences, and kinetic parameters, guiding optimization strategies with high accuracy.
Antibody Design
By leveraging advanced computational tools and data-driven approaches, we offer a comprehensive suite of services that encompass the entire spectrum of antibody design, from target identification to lead optimization.
Membrane Protein Design
Our AI-based platform enables us to simulate the behavior of the designed membrane protein channel in a lipid bilayer environment. This allows us to assess its functional properties, such as ion permeability, pore size, and gating kinetics, providing valuable insights for experimental validation.
Miniproteins Design
Leveraging AI algorithms and molecular modeling simulations, we customize and optimize disulfide bond patterns to impart desired structural stability and bioactivity to the miniproteins, tailored to the intended application.
Structural Protein Design
Our unique AI platform can efficiently analyze protein sequences to predict antigenic regions, helping our clients identify potential vaccine and immunotherapy targets, saving them time and money.
To refine designs further, we utilize protein engineering tools and software such as:
| Rosetta | For high-accuracy predictions and design of protein structures and complexes. |
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| CHARMM and GROMACS | Molecular dynamics simulations for elucidating folding pathways and energy landscapes. |
| PyMOL and Chimera | Visualization tools that facilitate structural analysis and interpretation. |
At CD ComputaBio, we harness cutting-edge computational techniques to facilitate the design, optimization, and analysis of proteins in a virtual environment. Utilizing advanced computer simulations, we aim to enhance protein functionality, stability, and specificity for various applications in pharmaceuticals, biotechnology, and research. If you are interested in our services or have any questions, please feel free to contact us.
Services