Careers

Computational Chemist

USA
Full-time

Job Description:

This position’s main responsibilities include Structure-Based Drug Design (SBDD), Ligand-Based Drug Design (LBDD), support of hit expansion, hit-to-lead, lead optimization and molecular docking. Proficiency in one of the benchmark drug discovery packages, e.g., Schrodinger, OpenEye, MOE or Cresset, is a must.

Key responsibilities:

+ Perform structure- and ligand-based Drug Design
+ Perform protein:small molecule and protein:protein docking
+ Perform virtual screening of molecular databases
+ Support hit-to-lead campaigns and integration of the biological data
+ Perform lead optimization for further ligand refinement

Education:

+ Ph.D. in relevant discipline with a minimum of 2 years of industry experience

Requirements:

+ Expertise in molecular modeling techniques, protein docking methods including induced-fit docking
+ Extensive knowledge in molecular or structural biology and biophysics
+ Experience in the application of statistical methods to evaluate properties of studied biological systems
+ Ability to learn and implement new modeling techniques
+ Good programming skills
+ Good communication skills and aptitude for teamwork and collaboration with experimentalists
+ Attention to detail and critical thinking capabilities
+ Excellent planning, execution, and organizational skills

* Not accepting calls from applicants.

Apply today!